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Studies to Advance Autism Research and Treatment (STAART) Network
As one of the responses to the Children's Health Act of 2000, NIH established the STAART Network. Although the Act called for at least five centers of excellence in autism research, the five NIH Institutes involved in the NIH Autism Coordinating Committee (NIMH, NICHD, NINDS, NIDCD, & NIEHS) funded eight centers, all of which focus on the causes, diagnosis, early detection, prevention, and treatment of autism. Each center supports three or more research projects, with at least one study focused on treatment. In addition, the centers engage in multi-site clinical trials and collaborate through meetings, interest groups, and data sharing.
About the CPEA Network
Boston University, MA
Kennedy Krieger, Baltimore, MD
Mount Sinai, New York, NY
University of California, Los Angeles
University of North Carolina, Chapel Hill
University of Rochester, NY
University of Washington, Seattle
Yale University, New Haven, CT
STAART
Title: Electrophysiological and fMRI Studies of Face Processing in Autism
Lead Center: University of Washington
Description: This project was designed to study the brain bases of one of the most basic aspects of social cognition, face processing. Measures of brain function assess both (1) the temporal aspects of face processing, using face-sensitive ERP component, N170, and (2) the spatial organization of brain function, using fMRI. We are also examining whether these brain function measures are correlated with measures of attention. These studies will test a neurocognitive model of face processing abnormalities in autism.

Abnormal functional connectivity in autism spectrum disorders during face processing

Abnormalities in the interactions between functionally linked brain regions have been suggested to be associated with the clinical impairments observed in autism spectrum disorders (ASD). We investigated functional connectivity within the limbic system during face identification; a primary component of social cognition, in 19 high functioning adults with ASD and 21 age-and IQ-matched control adults. Activation during identification of previously viewed ...