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Please click on one of the goals in the IACC Matrix below to
view the CPEA and STAART projects addressing the goal. For more information on
the IACC Matrix, click here
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| Blue = neuroscience | Green = school and community interventions |
| Gray = epidemiological studies | Orange = early intervention |
| Purple = Specific treatments | Red = Characterization of autism (i.e. phenotype) |
| Pink = screening | Black = Role of the Environment in Autism and remaining items |
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| | Short Term Goals (1-3 years) | Medium Term Goals (3-6 years) | Long Term Goals (7-10 years) |
High
Risk
Research |
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Medium
Risk
Research |
| 3. |
Resources established for genotype/phenotype studies (i.e. bioinformatics, genetic repository) |
| 4. |
Existing data studied to begin to characterize the autism phenome, as part of the larger Phenome Project |
| 5. |
Infrastructure, such as enhanced brain acquisition, established for neuropathological investigations, to characterize the morphological aspects of the pathophysiology of autism |
| 6. |
Technology and infrastructure developed for multi-site in vivo imaging studies, to identify the neuropathology of autism |
| 7. |
Randomized clinical trial developed for the evaluation of the effectiveness of early behavioral intervention and factors predicting response to intervention |
| 8. |
Innovative intervention strategies developed to improve outcomes in the school and community settings throughout the lifespan, including transitions (e.g. academic functioning, social and adaptive behavior, family functioning, employment) in collaboration with the Department of Education and other federal agencies |
| 9. |
Develop research on implementing early identification of children with autism in community settings, and employ a population-based longitudinal cohort |
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| 19. |
Biological and/or behavioral markers identified to develop indices of risk for the development of autism in infants |
| 20. |
Multi-site randomized clinical trial implemented to identify moderators and effective ingredients (e.g. dose, intensity, mode of delivery, age of onset) of early intervention treatments |
| 21. |
Intervention methods for infants and toddlers developed, to lower the age for which there are efficacious interventions |
| 22. |
Neuropathology of autism characterized, to identify brain structures and functions associated with autism |
| 23. |
Developmental time course characterized for alterations in brain structures and connections in autism |
| 24. |
Continue formulating, evaluating and implementing appropriate efficacious intervention strategies incorporating research-based findings to improve outcomes in the school and community settings throughout the lifespan, including transitions (e.g. academic functioning, social and adaptive behavior, family functioning, employment) in collaboration with the Department of Education and other federal agencies |
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Low
Risk
Research |
| 10. |
Autism Phenome Project defined and planned |
| 11. |
Outcome measures improved, to enhance their effectiveness in evaluating treatment studies |
| 12. |
Twin resource developed, to study heritability and environment factors influencing autism |
| 13. |
Effective interventions expanded, disseminated and implemented to improve outcomes in the school and community settings throughout the lifespan, including transitions (e.g. academic functioning, social and adaptive behavior, family functioning, employment) in collaboration with the Department of Education, and other federal agencies, such as the Department of Labor and Social Security Administration |
| 14. |
Research Communication Network (both local and national) developed to disseminate findings among researchers and the public to increase ongoing communication |
| 15. |
Evaluate sensitivity and specificity of existing screening tools, and continue developing efficacious screening measures |
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| 25. |
Multi-site longitudinal study of subsequent pregnancies and infant siblings of children with autism implemented, to identify risk factors, broader phenotype and early characterization of autism |
| 26. |
Neural circuitry and neurochemistry defined for several functions impaired in autism |
| 27. |
Innovative and newly developed intervention strategies evaluated, implemented and disseminated to improve outcomes in the school and community settings throughout the lifespan, including transitions, (e.g. academic functioning, social and adaptive behavior, family functioning, employment) in collaboration with the Department of Education and other federal agencies |
| 28. |
First-generation, intensive, community-based prevalence studies with clinical evaluations implemented, to have initial data for detecting changes in prevalence of autism |
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